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Data Visibility (Show Your Work) Data Visibility (Show Your Work) Good: Full HPLC chromatograms + MS spectra for the exact batch Bad: Typed summaries like Purity: 99% with no raw data C

doi:10.7326/0003-4819-87-2-202

Sarkar S, Deyoung T, Ressler H, Chandler W

Scale-Up and High-Throughput Reconstitution Methods Standardize the solvent batch, volume added, and incubation time across every vial so each preparation matches

Similarly, in the cortex of wobbler mouse model of ALS, reduced GABA mediated inhibition in the layer 5 pyramidal neurons as a result of loss of GABAergic interneurons was shown, resulting in cortical excitability (Nieto-Gonzalez et al., 2011)