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Given the lack of comparative studies on the interaction between chelators and efflux transporters, our aim was to establish a comprehensive experimental model to evaluate and compare the effects of the three major MDR ABC transporters on the toxicity of metal chelators

[96] However, citrate-capped gold nanoparticles sizes 8-37 nm were found to be lethally toxic for mice, causing shorter lifespans, severe sickness, loss of appetite and weight, hair discoloration, and damage to the liver, spleen, and lungs

Associations between amino acids and bone mineral density in men with idiopathic osteoporosis

Furthermore, our enzyme kinetic assays showed that although 6-hydroxy-FAD-reconstituted hFSP1 exhibited lower affinities ( K m ) for NADH and CoQ 1 than FAD-reconstituted hFSP1, the NADH oxidation activity ( k cat ) of 6-hydroxy-FAD-reconstituted hFSP1 was higher than that of FAD-reconstituted hFSP1 (Supplementary Table 3)

Altered metabolites in newborns with persistent pulmonary hypertension