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Description

Thiamine HCL, biotin,

As the lens ages, crystallins undergo several post-translational modifications, including phosphorylation, glycation, and oxidation, which can lead to protein unfolding, aggregation, and precipitation [27,28]

PMID: 37302615 Mater Today Adv2023, 17: 100336

A Phase I safety trial evaluating the administration of synthetic T4 at massive doses ranging from 42mg to 1260mg over 14 days demonstrated excellent tolerability with no severe toxicities or serious adverse events reported in healthy adults