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Description

Silymarin (100 mg/kg) decreased cardiac fibrosis, collagen deposition, and dysfunction in diabetic mice, whereas silibinin used ERK1/2 MAPK signalling to control hypertrophic responses in cardiomyocytes ( 3.3.3 Renoprotective activity The oxidative and inflammatory burden to which the kidney is exposed is high due to its role in xenobiotic detoxification

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Quantification of ROS by DCFDA Fluorescence Cells were plated in 24-well clear tissue culture-treated (Genesee Scientific, San Diego) plates and compounds were pre-treated as stated for 16 h

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