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To examine the role of this residue from a biochemical perspective, we constructed the recombinant GpoA Cys36Ala -His x6 mutant using a directed mutagenesis protocol [26]

Despite setbacks in biodistribution, toxicity, and scale-up manufacturing challenges, ongoing research is still optimizing nanoparticle design for targeting specificity and clinical applicability [110]

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doi: 10.1073/pnas.96.2.721 85 WuL.ZhouX.LiT.HeJ.LinX.HuangL.et al